Safety
While in a foreign country, you are subject to that country’s laws and regulations, which sometimes differ significantly from those in your home country and may not afford the protections available to the individual under your home jurisdiction. Penalties for breaking the law can be more severe for similar offenses. Persons violating Panamanian laws, even unknowingly, may be expelled, arrested or imprisoned. Penalties for possession, use, or trafficking in illegal drugs in Panama are strict, and convicted offenders can expect jail sentences and heavy fines. If you are not a money launderer, drug seller or terrorist you will find Panama to have a relatively laid back attitude towards crime compared to North America, Australia and the EU.
In general while in Panama the average Expat is unlikely to run afoul of the law. In Panama business has not been criminalized as it has in the USA, UK, Australia and many other countries. The vast majority of the law enforcement people in Panama devote their time and energies to real crime, drug traffic enforcement and crime prevention. There is not a whole lot of victimless crime prosecution in Panama.